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Best American Restaurants in South Louisville

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74 restaurants available nearby

A photo of Swizzle restaurant
4.5
Awesome(2109)
Price: Expensive
• American • Downtown Louisville
Booked 39 times today
Swizzle, nestled in the vibrant heart of Downtown Louisville, is a premier destination for cocktail enthusiasts. Celebrated for its "sexy, swanky" ambiance and panoramic river views, Swizzle elevates the cocktail bar experience. Guests rave about the "retro tone" of the drink menu, which features meticulously crafted classic cocktails and seasonal specialties. The Swizzle Big Bar area is a social hotspot, offering enticing happy hour specials and delightful bar bites. Reviewers consistently praise the quality of the drinks, like the "spot on" smoky Old Fashioned and the refreshing Sting Like a Bee. With such endorsements and its superb setting, Swizzle is a must-visit for an authentic and memorable cocktail experience in Louisville.
A photo of Le Moo restaurant
4.6
Exceptional(5690)
Price: Expensive
• American • Highlands - Bardstown Rd / Taylorsville Rd
Booked 85 times today
Le Moo in Louisville’s trendy Highlands neighborhood is a standout gem among Contemporary American eateries. Celebrated on Food Network’s list as one of the top 25 steakhouses in America, Le Moo offers a distinctive dining experience with its unique Vintage Louis Vuitton booth and an impressive array of steaks, including a Tomahawk Ribeye that's a must-try. Reviewers rave about the quality of the food and service, with one guest proclaiming, "Le Moo never disappoints... If you are in the mood for the best steak you've ever had... Le Moo is the place to go." Whether you’re celebrating a special occasion or enjoying a luxurious brunch, Le Moo promises an extraordinary culinary journey with dishes that are "akin to a religious experience."
A photo of Proof on Main restaurant
4.5
Awesome(3737)
Price: Expensive
• American • Downtown Louisville
Booked 25 times today
The ingredients in our menus reflect the region’s sustainable farmers and producers with a soulful and honest approach showcasing the bounty of the Ohio River Valley. Housed in five historic buildings in downtown Louisville, Proof on Main is part of 21c Museum Hotels, the award-winning boutique hotel and restaurant group. The dining room is one of the most striking public spaces in the city, with rotating, contemporary art exhibitions by local and internationally-acclaimed artists alike.
A photo of Vincenzo's Italian Restaurant restaurant
4.8
Exceptional(3681)
Price: Expensive
• American • Downtown Louisville
Booked 23 times today
Vincenzo's Italian Restaurant in Downtown Louisville redefines American dining with its exemplary approach to classic Italian cuisine, prepared with a distinct American flair. Established in 1986 and highly acclaimed, including being named the Best Italian Restaurant in Kentucky by The Daily Meal in May 2020, Vincenzo's embodies the quality and authenticity of American food culture. Diners consistently praise their experiences: "The food was exceptional," and "Service was welcoming, well-timed, and reminiscent of the best classic Italian traditions." The restaurant's commitment to table-side food preparation and flaming specialty desserts further enhances the dining experience, making every visit memorable. As one diner enthusiastically noted, "This is a fabulous restaurant in every regard. My favorite in Louisville, perhaps anywhere!"
A photo of Lobby Bar & Grill at the Brown Hotel restaurant
4.6
Exceptional(1078)
Price: Expensive
• American • Downtown Louisville
Booked 28 times today
Come enjoy the historic lobby of The Brown Hotel in our Lobby Bar and Grill. Contemporary cuisine meets historic opulence at The Brown Hotel’s spectacularly beautiful, and classic lobby setting. A popular spot for the next generation of Louisville merrymakers, this glamorous, gilded space balances its history with modern touches and sophisticated tastes. Our menu includes a mix of classic and contemporary dishes, but our signature Hot Brown is rated as Kentucky's most popular dish. Enjoy our Hot Brown, and other signature items with a classic Old Fashion. Our bar features well-crafted cocktails and an highly rated bourbon menu. Finish your experience with Louisville's original dessert, the Derby pie. Reservations are for the Lobby Bar and Grill.
A photo of Doc Crow's Southern Smokehouse & Raw Bar restaurant
4.4
Awesome(1504)
Price: Moderate
• American • Downtown Louisville
Booked 37 times today
Doc Crow's Southern Smokehouse & Raw Bar in downtown Louisville is a haven for barbecue enthusiasts, offering a delightful fusion of traditional Southern cooking and authentic barbecue flavors. Patrons rave about the "best BBQ I've had in a long time," particularly praising the pulled pork sandwich and the perfectly crafted Old Fashioned. The restaurant's commitment to quality is evident, with visitors noting that the brisket was "the best they'd tasted." Amidst a cozy atmosphere complemented by an extensive bourbon list, Doc Crow's not only promises great food and drinks but also a true taste of Southern hospitality. Whether you're a local or just passing through, Doc Crow's is a must-visit for a memorable barbecue experience.
A photo of The Café Southern Kitchen & Cocktails restaurant
4.4
Awesome(86)
Price: Moderate
• American • Downtown Louisville
Booked 30 times today
The Café in Downtown Louisville is a beacon of authentic American cuisine with a delightful Southern twist. Celebrated as the LEO Weekly Readers' Choice #1 Lunch Spot, this gem offers a rich menu from breakfast to dinner, including comfort food classics and scratch-made entrées. Diners rave about the "always delicious" food and "phenomenal" service, highlighting dishes like the "amazing" Huevos Rancheros and the best BLT ever tasted. The Café's ambiance, enhanced by live piano music, creates a perfect backdrop for enjoying their extensive bourbon and wine list. A visit here promises generous portions, a warm atmosphere, and an unforgettable dining experience, making it a must-visit in Louisville.
A photo of Beyond the Sun Restaurant restaurant
4.1
Excellent(139)
Price: Moderate
• American • Highlands - Bardstown Rd / Taylorsville Rd
Booked 16 times today
Discover the culinary delights of Beyond the Sun Restaurant, nestled in the vibrant Highlands area of Louisville. This dining gem offers a captivating menu that truly embodies the essence of Global, International cuisine. From succulent steaks and creamy fettuccine to fresh seafood and delightful bar food upstairs, every dish is crafted to perfection. Guests rave about the restaurant’s "amazing service" and the "delicious" food, highlighting the fusion of flavors that cater to every palate. Whether it's the live jazz atmosphere or the extensive selection of bourbon and tequila, Beyond the Sun promises a dining experience that is both "exceptional" and "totally worth visiting." Indulge in a world-class meal where the "food choices were plenty" and each visit feels like a special occasion.
A photo of Varanese restaurant
4.7
Exceptional(4604)
Price: Moderate
• American • Frankfort Ave - Crescent Hill
Booked 28 times today
Varanese, nestled on Frankfort Ave in Louisville's vibrant Crescent Hill, is celebrated for its exceptional Steak cuisine. This gem offers an eclectic menu that shines with its signature steak dishes, expertly crafted to satisfy the most discerning palates. Diners consistently rave about the quality and flavor of the steak, describing it as "always good" and highlighting it as a standout. One glowing review shares that "the flat iron steak was excellent," underscoring the culinary prowess that Varanese brings to its steak offerings. With its commitment to fresh ingredients and creative flair, Varanese not only promises but delivers an extraordinary dining experience where the steak is not just a meal but a memorable event. The inviting atmosphere, complete with live music and a modern American ambiance, makes each visit uniquely delightful.
A photo of High Stakes Rooftop Grill restaurant
4.0
Excellent(81)
Price: Expensive
• American • West Louisville
Booked 14 times today
High Stakes is a modern take on the classic American grill showcasing culinary traditions and flavorsome grilling techniques with a dedication to high-quality ingredients. Paying homage to the come-from-behind winners in life, sports, history, and the arts – celebrating all the unimaginable photo finishes, strivers, and unlikely underdog winners that have made this great country what it is today. Here’s to the winners, the higher the stakes, the more you own that moment in time.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Elizabethvip
    Chicago / Illinois •36 reviews
    5.0
    Dined 1 day ago
    Vincenzo is consistently over the top. Our server Rubin is excellent and the food over the top!!!
    More info
    Vincenzo's Italian RestaurantPrice: Expensive• Italian• Downtown Louisville
    4.8
  • Dana
    New York City •1 review
    5.0
    Dined 3 days ago
    What a WOW view from one of the rotating dining rooms! We thoroughly enjoyed splurging for our anniversary dinner at Swizzle. The calamari appetizer was excellent, as was the wedge salad which they kindly split for us. And basket of warm bread - yum! My husband now lists their Tomahawk Pork Chop in his top ten - super tender, perfectly cooked. I had the scallops - also perfectly cooked with the grits, peas, and fried onions accompaniments - wonderful. Considering it was a super busy night at the restaurant, we felt very well taken care of by the wait staff. Also, if you aren't staying at the hotel or Ubering, use the restaurant valet for $10.00. A great deal for parking, and our car was waiting for us at the curb when we were done with dinner.
    More info
    SwizzlePrice: Expensive• Contemporary American• Downtown Louisville
    4.5
  • Joshua
    Chicago / Illinois •1 review
    5.0
    Dined 4 days ago
    What a menu! Make sure to start with the amuse bouche, the mini arancini was perfect. The mushrooms appetizer is unlike any I've had; warm, cold, crispy, umami, tangy, creamy. The trout was warm and briney but offset by a beautiful char on the skin. Fantastic dining experience, exceptional vibes. Can't wait to come back next time I'm in Lousiville.
    More info
    Proof on MainPrice: Expensive• Contemporary American• Downtown Louisville
    4.5
  • Alicia
    Central Kentucky •7 reviews
    5.0
    Dined 4 days ago
    Overall, we were very happy with everything at Le Moo. The only thing I would not write this experience as a five out of five is the speed of getting our food. It took quite a while to get our appetizer and soup. And within about two minutes of receiving those items, our entrées arrived. I don’t mind if we are still finishing up our appetizer when we get our entrée, but at this point, we had barely begun. And to be honest, the table really just wasn’t big enough for all of our items at once. Otherwise everything was superb. And even though it took a little bit to get our appetizer and soup, our server was very good. I could tell she was very busy. Also, because they are celebrating their 10th birthday, you get a toast of champagne when they walk you to your table. That was an awesome touch. Thank you so much for that. We will be back for sure!
    More info
    Le MooPrice: Expensive• Steakhouse• Highlands - Bardstown Rd / Taylorsville Rd
    4.6
  • Joelvip
    Central Kentucky •28 reviews
    5.0
    Dined 5 days ago
    Our server was excellent and the food was delicious. We went for lunch and the food was out promptly. Great place to go.
    More info
    The Café Southern Kitchen & CocktailsPrice: Moderate• American• Downtown Louisville
    4.4
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