Skip to main content

Home
United States
San Diego

Best Cocktail Bars in Serra Mesa

Price

€€
€€€
€€€€

Regions

East CountySan Diego

Areas

Banker's HillCoronadoDowntown / GaslampHillcrestLa MesaLittle Italy

Top Rated

CharmingFancyGood for business mealsGood for groupsGood for special occasionsGreat for brunch

Dining Options

All dining options

Delivery only

Takeaway only

Seating options

BarCounterStandardHigh TopOutdoor

Award-winning

MICHELIN

Accessibility

Gender-neutral toiletWheelchair access

31 restaurants available nearby

A photo of Wormwood restaurant

1. Wormwood

4.6

Exceptional(827)

€€€€Price: Very Expensive

• Cocktail Bar • North Park

Booked 11 times today

Wormwood in North Park, San Diego, redefines Mediterranean dining with its unique blend of French elegance and bohemian charm. This cozy haven is a neighborhood gem celebrated for its "wonderful flavors and combinations" that leave patrons coming back for more. The menu, featuring dishes like wagyu tartare and fresh oysters, showcases a remarkable fusion of local flavors and Mediterranean craftsmanship. Reviewers rave about the "phenomenal" food and "excellent" service, making each visit a delightful culinary adventure. Whether enjoying the enchanting patio or the speakeasy vibe of the Secret Garden, Wormwood promises a memorable experience that "never disappoints."

A photo of Botanica restaurant

2. Botanica

4.6

Exceptional(46)

€€€€Price: Moderate

• Cocktail Bar • North Park

Booked 12 times today

Botanica, nestled in the vibrant neighborhood of North Park, San Diego, is a haven for those who cherish exquisite Tapas and Small Plates. The restaurant crafts an unforgettable experience with its delectable array of small bites that perfectly complement their artisanal cocktails. Patrons rave about the "creative small plates" that elevate any dining occasion with their sophisticated flavors. The ambiance is both lively and intimate, making it an ideal spot for a cozy yet vibrant dining experience. Praised for its "delicious food" and "amazing service," Botanica ensures that every visit feels like a celebration of culinary artistry and exceptional hospitality.

A photo of Cocina de Barrio North Park restaurant

3. Cocina de Barrio North Park

4.5

Awesome(9)

€€€€Price: Moderate

• Cocktail Bar • North Park

Booked 6 times today

*Brunch hours are on a walk-in basis only.Cocina de Barrio by Chef Jose J. FloresWelcome to Cocina de Barrio, the newest modern-urban Mexican restaurant located in North Park! We are proud to feature the culinary richness of Oaxaca as well as other Mexican regions. Stop by and enjoy our bar stocked with plenty of tequila and mezcal selections, beer, and wines sourced from Valle Guadalupe.Don't forget to join us during our daily brunch (where we add a Mexican kick) and our happy hour every Monday-Friday from 3-5pm! Stay Chido!

A photo of Blanco Cocina + Cantina – Fashion Valley restaurant

4. Blanco Cocina + Cantina – Fashion Valley

4.7

Exceptional(569)

€€€€Price: Moderate

• Cocktail Bar • Mission Valley

Booked 12 times today

Blanco Cocina + Cantina – Fashion Valley is a standout destination in Mission Valley, San Diego for those seeking an exceptional cocktail bar experience. Known for its vibrant atmosphere and refreshing drinks, Blanco’s cocktail bar is a "perfect spot for sipping margaritas," as delighted patrons often rave. The spicy skinny margaritas are a particular highlight, earning consistent praise for their bold flavors and delightful presentation. With an inviting outdoor area featuring comfortable seating and heat lamps, it’s an ideal place to unwind. Whether you're enjoying a casual hangout or celebrating a special occasion, Blanco ensures your cocktail experience is nothing short of extraordinary.

A photo of NOLA on 5th restaurant

5. NOLA on 5th

4.3

Awesome(85)

€€€€Price: Moderate

• Cocktail Bar • Hillcrest

Booked 10 times today

NOLA on 5th in San Diego's vibrant Hillcrest neighborhood is a cocktail bar that truly captures the spirit of New Orleans. Known for its "terrific drinks," the bar offers a wide selection of inventive cocktails alongside classic favorites like the Hurricane, which "brought us back to Bourbon Street." Guests rave about the "bottomless mimosas" that are perfect for brunch, making it an ideal spot for both casual afternoons and lively evenings. The bar's ambiance complements its authentic flavors, with guests describing the atmosphere as "upbeat" and the service as "phenomenal." Whether you're a local or visiting, NOLA on 5th promises an unforgettable cocktail experience.

A photo of C-Level restaurant

6. C-Level

4.7

Exceptional(5038)

€€€€Price: Moderate

• Cocktail Bar • Downtown

Booked 124 times today

C-Level in Downtown San Diego offers an exceptional Seafood dining experience like no other. Nestled on stilts with breathtaking views of the San Diego Bay and skyline, this restaurant combines stunning ambience with culinary excellence. Diners rave about the fresh and flavorful Seafood dishes, with one guest noting, "The seafood was fresh and hit all the right spots." Highlights such as the Lobster Mac & Cheese and cedar plank salmon are among the favorites. Service is consistently praised, ensuring that every visit is memorable. Whether for a special occasion or a casual outing, C-Level promises "delicious food and an unbeatable view."

A photo of Wilma's Carousel Bar restaurant

7. Wilma's Carousel Bar

4.7

Exceptional(91)

€€€€Price: Expensive

• Cocktail Bar • Little Italy

Booked 31 times today

Wilma's Carousel Bar, nestled in the vibrant Little Italy of San Diego, offers an enchanting dining experience with its Contemporary French and American cuisine. Executive Corporate Chef Brian Redzikowski masterfully crafts French-Creole inspired dishes that leave diners raving about the "crispy and perfectly seasoned fries" and the "juicy, flavor-packed burger." The culinary journey is complemented by the imaginative cocktails curated by Beverage Director Eric Johnson, making each visit a delightful escape. Reviews consistently highlight the restaurant’s "fantastic food, outstanding service, and lively atmosphere," promising an unforgettable dining experience that captures the essence of contemporary culinary excellence. Don't miss the beignets—"heavenly, light, and perfectly sweetened."

A photo of Nolita Hall restaurant

8. Nolita Hall

4.3

Awesome(806)

€€€€Price: Expensive

• Cocktail Bar • Little Italy

Booked 51 times today

Nolita Hall, located in the vibrant neighborhood of Little Italy, San Diego, delivers an exceptional Pizza Bar experience that transports diners straight to the heart of Italy. Known for its Fiori woodfire oven, this beloved spot crafts pizzas that are nothing short of spectacular. Patrons rave about the "pepperoni pizza with honey" as being "awesome," highlighting the unique and delightful flavor combinations that set Nolita Hall apart. The atmosphere is a perfect blend of fun and elegance, with many calling it a "great place to watch a sports game" while indulging in top-quality pizzas. It's a must-visit for pizza lovers seeking authentic taste and vibrant ambiance.

A photo of The Prado at Balboa Park restaurant

9. The Prado at Balboa Park

4.6

Exceptional(7981)

€€€€Price: Moderate

• Cocktail Bar • Downtown

Booked 86 times today

Nestled in the heart of San Diego's historic Balboa Park, The Prado stands out not only for its California cuisine but also as an exceptional Cocktail Bar. The ambiance is warm and enchanting, setting the perfect backdrop for an unforgettable cocktail experience. Guests have raved about the "excellent cocktails," with standout mentions like the pradoritas, which are described as "the best" margaritas around. The staff's knowledge and passion for mixology ensure that each drink is crafted to perfection, adding to the charm of this iconic location. Whether you're a cocktail aficionado or a casual diner, The Prado promises a delightful and memorable experience.

A photo of Roman Wolves restaurant

10. Roman Wolves

4.6

Exceptional(368)

€€€€Price: Moderate

• Cocktail Bar • Little Italy

Booked 64 times today

Roman Wolves in Little Italy, San Diego, is a shining gem for Cocktail Bar enthusiasts. This vibrant establishment is celebrated for its exquisite cocktails, with the Hugo Spritz receiving rave reviews as "incredible" and leaving patrons eager for more. The talented bartenders at Roman Wolves ensure that each drink is a masterpiece, complementing the rich Italian culinary experience. Diners frequently commend the bar's atmosphere, describing it as lively and welcoming, perfect for both intimate gatherings and spirited celebrations. If you're seeking a memorable cocktail experience in the heart of San Diego, Roman Wolves is the place to be!

1
2
3
4

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you

From verified diners like you

L
LupitaVIP
San Diego •10 reviews
5.0
Dined 1 day ago
Service was excellent, drinks were absolutely delicious and food was great. The place is kinda of small but very chic.
More info
BotanicaPrice: Moderate• Cocktail Bar• North Park
•
4.6
I
Irianny
San Diego •3 reviews
5.0
Dined 2 days ago
A fun experience! Came here for Valentine’s Day with reservations and had a smooth experience. Because of the holiday they only had a 5 tasting course. It was a bit packed understandably. The drinks were amazing! The food was a culinary experience. The service was on par. We were there for close to 3 hours however because the food came out very slow, however they gave us a discount because of it without us even asking. Amazing attention to detail!
More info
WormwoodPrice: Very Expensive• French• North Park
•
4.6
S
Susan
Washington, D.C. Area •8 reviews
4.0
Dined 4 days ago
It's a small place with the front space filled with the bar. It was so cold that we had to keep our coats and fleece on! The food was hot, tasty and came out quickly. We would definitely eat there again.
More info
NOLA on 5thPrice: Moderate• Creole / Cajun / Southern• Hillcrest
•
4.3
H
Henry
San Diego •5 reviews
5.0
Dined 6 days ago
I cannot recommend Cocina de Barrio more highly. Everything about the experience was superb, especially the food and the service. The staff is attentive and responsive. The food is stellar, fresh and extremely flavorful!
More info
Cocina de Barrio North ParkPrice: Moderate• Mexican• North Park
•
4.5
M
May
San Diego •25 reviews
5.0
Dined on 28 Jan 2025
Everything was great at Blanco - all the dishes were good, service was attentive, ambience nice. The Restaurant Week menu was a REALLY good value and everyone enjoyed their food. (We were a party of 6)
More info
Blanco Cocina + Cantina – Fashion ValleyPrice: Moderate• Mexican• Mission Valley
•
4.7

Explore OpenTable

Area
Cuisine nearby
Cocktail Bar cuisine

Serra Mesa

Cocktail Bar

National City
Carlsbad
South Park
La Jolla
Mission Valley
Hillcrest
Banker's Hill
La Mesa
Ocean Beach
Mission Bay
Sorrento Mesa
Tierrasanta
Pacific Beach
Coronado
Chula Vista / Bonita
Linda Vista
Torrey Pines
Kearny Mesa
Mission Hills
Serra Mesa

Discover

Reserve for Others
Restaurants near me
Delivery near me
Restaurants Open Now

OpenTable

About Us
Blog
Careers

More

OpenTable for iOS
OpenTable for Android
Contact Us

Our sites

OpenTable.com
OpenTable.jp
OpenTable.de
OpenTable.es
OpenTable.ca
OpenTable.hk
OpenTable.sg
OpenTable.nl
OpenTable.com.mx
OpenTable.co.uk
OpenTable.com.au
OpenTable.ae
OpenTable.co.th
OpenTable.it
OpenTable.com.tw
OpenTable.fr

Businesses

Delight more diners
Restaurant Blog

Join us on

Privacy policy
Terms of Use
Impressum
Cookies and Interest-Based Ads
Cookie Preferences

Copyright © 2024 OpenTable International Ltd. Alphabeta Building, 14-18 Finsbury Square, London EC2A 1AH - All rights reserved.

OpenTable is part of Booking Holdings, the world leader in online travel and related services.