Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Seafood Restaurants in Medical Center

Price
Regions
Areas
Top Rated
Dining Options
Seating options
Accessibility

27 restaurants available nearby

A photo of Myron's at Alon Town Center restaurant
4.9
Exceptional(4700)
Price: Expensive
• Seafood • North San Antonio
Booked 17 times today
Myron's at Alon Town Center is a hidden gem in North San Antonio, known for its superb Seafood cuisine that rivals its renowned steaks. Diners rave about the "magnificent Alaskan king crab legs" and perfectly seasoned lobster tails, which are described as "the best I've ever had." The seafood specials, like the succulent shrimp and expertly cooked scallops wrapped in bacon, showcase Myron's commitment to quality and authenticity. With each dish crafted to perfection, Myron's offers a delightful dining experience where Seafood lovers can indulge in flavors that are both fresh and impeccably prepared, making it a must-visit destination.
A photo of Red Lobster - San Antonio - NW Loop 410 restaurant
4.4
Awesome(18)
Price: Moderate
• Seafood • North San Antonio
Elevate your day at Red Lobster, where fun meets fancy and every meal is a celebration. Whether you’re marking a special occasion or treating yourself or your crew, Red Lobster is the perfect place to enjoy all your seafood favorites. Dive into our signature shrimp, wild caught lobster and crab, and more. Plus, a variety of fish and popular non-seafood items like our Cajun Chicken Linguini Alfredo. Looking for a showstopper? Create Your Own Ultimate Feast or select a Live Maine Lobster straight from the tank. Or explore our Daily Deals with a different special available each weekday at a price you’ll love. Toast the day with Signature Cocktails including Lobster Punch and Main Deck Margarita Flights to make any moment feel festive. You won’t want to miss our newest menu items or special promotions like Lobsterfest and Crabfest. Reserve online today. Group Dining, To Go, or Catering options. For parties of 11+, please call.
A photo of Perry's Steakhouse & Grille - San Antonio restaurant
4.6
Exceptional(9510)
Price: Expensive
• Seafood • La Cantera
Booked 72 times today
Perry's Steakhouse & Grille - San Antonio is a beacon of authentic American cuisine nestled in the lively La Cantera area. Renowned for its "exceptional" pork chops and "outstanding" service, Perry's offers a dining experience that consistently delights locals and visitors alike. Guests rave about the "juicy, flavorful, and tender" meats, which are expertly crafted by the skilled chefs visible from the spacious, open dining area. The vibrant atmosphere, underscored by the popular Bar 79® with its floor-to-ceiling windows, enhances every visit, making Perry's a top choice for both casual and special occasions. "Perry's never disappoints," ensuring a memorable American culinary experience.
A photo of Chart House Restaurant - Tower of the Americas restaurant
4.4
Awesome(16745)
Price: Moderate
• Seafood • Downtown
Booked 171 times today
Chart House Restaurant - Tower of the Americas in Downtown San Antonio offers an exquisite American dining experience. Renowned for serving up fresh seafood and succulent steaks, the restaurant has been praised for its "absolutely fantastic" cuisine and service that goes "above and beyond." Guests rave about the cedar plank salmon and prime rib, describing their meals as "delicious" and "top tier." The stunning panoramic views from 750 feet in the air make dining here unforgettable. With a rich heritage of over 50 years, Chart House continues to redefine authentic American cuisine, making it a must-visit for both locals and visitors.
A photo of Eddie V’s – Wildfish – San Antonio restaurant
4.8
Exceptional(6739)
Price: Very Expensive
• Seafood • North San Antonio
Booked 44 times today
Eddie V’s – Wildfish – San Antonio is a premier destination for steak enthusiasts, offering "the best steakhouse experience in town." Located in North San Antonio, this luxurious dining venue is renowned for its prime center-cut steaks, expertly hand-carved and broiled to perfection. The restaurant's commitment to quality and authenticity shines through every dish, with patrons frequently praising the "stellar service and consistently top-notch food." Eddie V's creates unforgettable dining experiences, where memorable occasions are celebrated with exquisite steaks and a wine list recognized by Wine Spectator. Whether for a special celebration or an indulgent evening out, Eddie V’s promises an extraordinary steakhouse adventure.
A photo of Seasons 52 - San Antonio restaurant
4.8
Exceptional(760)
Price: Expensive
• Seafood • Alamo Heights
Booked 24 times today
Seasons 52 in Alamo Heights, San Antonio, is renowned for its exquisite Seafood cuisine, where freshness and flavor are at the core of every dish. Diners rave about the "outstanding meal" experiences, with specialties like the Chilean sea bass leaving a lasting impression. The restaurant’s menu is crafted with seasonal ingredients, ensuring that each Seafood offering is at its peak of quality and taste. Guests appreciate the "great fresh food" and the attention to detail in preparation, which is evident in every bite. With a commitment to providing lighter, naturally flavorful options, Seasons 52 stands out as a top choice for Seafood lovers.
A photo of Dean's Steak & Seafood restaurant
4.6
Exceptional(283)
Price: Very Expensive
• Seafood • Downtown
Booked 51 times today
Dean's Steak & Seafood in Downtown San Antonio offers an extraordinary seafood dining experience that is both authentic and of superior quality. Set in a historic 19th-century schoolhouse, this restaurant features a menu that showcases the finest seafood selections. Guests rave about the "perfectly prepared halibut" and the "superb round of oysters," highlighting the meticulous attention to detail in every dish. The ambiance is elegantly intimate, making it ideal for special occasions or an upscale dining experience. With impeccable service and a commitment to culinary excellence, Dean's Steak & Seafood is a must-visit destination for seafood lovers.
A photo of Bohanan's Prime Steaks and Seafood restaurant
4.8
Exceptional(8343)
Price: Very Expensive
• Seafood • Downtown
Booked 51 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio elevates seafood dining to an art form. Known for its "succulent seafood flown in fresh daily," the restaurant ensures that each dish bursts with authentic, ocean-fresh flavors. Diners rave about the "macadamia encrusted red snapper" and "outstanding salmon" that epitomize the exquisite quality of their seafood offerings. The AAA Four Diamond-rated restaurant pairs its seafood with impeccable service, creating an extraordinary dining experience. Located in a historic building near the River Walk, Bohanan's is a must-visit for seafood lovers seeking a memorable meal in a stunning, elegant setting.
A photo of BLÜ Prime Steakhouse restaurant
4.7
Exceptional(685)
Price: Very Expensive
• Seafood • North Central
Booked 32 times today
BLÜ Prime Steakhouse in North Central, San Antonio, excels in delivering exquisite Seafood cuisine that is both authentic and top-notch in quality. Diners rave about standout dishes such as the "hard to find good Maryland Crab Cake" and the "creamy lobster mac and cheese," which are described as "out of this world!" The Chilean sea bass is another favorite, praised for its outstanding flavor. The restaurant’s commitment to fresh, high-quality ingredients shines through in every dish, making it a must-visit for Seafood lovers. The exceptional service and inviting ambiance further enhance an unforgettable dining experience at BLÜ Prime Steakhouse.
A photo of Bob's Steak & Chop House - San Antonio restaurant
4.8
Exceptional(3178)
Price: Very Expensive
• Seafood • Northwest
Booked 12 times today
Bob's Steak & Chop House in San Antonio isn't just renowned for its top-tier steaks—it's also a hidden gem for seafood lovers. Located in the heart of Northwest San Antonio, Bob's offers an exceptional seafood experience that rivals even the finest steakhouses. Guests rave about the "tuna tartare" and the "shrimp scampi," which is described as "enough for two" and bursting with flavor. The "fried lobster" appetizer is a must-try, leaving diners in awe of its exquisite taste. With an atmosphere that exudes elegance and a reputation for impeccable service, Bob's ensures every seafood dish is a delightful culinary journey.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Sara
    San Antonio •5 reviews
    5.0
    Dined today
    The waiter was extremely exceptional. Everything was delicious. Service is great. Had a wonderful experience.
    More info
    Perry's Steakhouse & Grille - San AntonioPrice: Expensive• Steakhouse• La Cantera
    4.6
  • Joycelyn
    Houston •1 review
    5.0
    Dined 1 day ago
    The entire experience was amazing! From the entry into the Tower to our exit we were treated with respect and kindness. Our waiter was excellent and very attentive. He acknowledged my boyfriend’s birthday several times. The food took a bit off a wait too receive it but when it came, it was worth the wait. Everything was great! Everything was also reasonably priced on the lunch menu.
    More info
    Chart House Restaurant - Tower of the AmericasPrice: Moderate• Seafood• Downtown
    4.4
  • James
    San Antonio •14 reviews
    5.0
    Dined 4 days ago
    Went with my wife for Valentine's dinner. She started with seafood bisque which she said was possibly the best she's had. We had 8 oz filet and ribeye for our entrée. Both were cooked perfectly, flavorful and excellent quality steaks. I recommend the scallop potatoes as the side. Finished with sharing the warm brownie and coffee. Myrons has been our Valentine's tradition since we moved here 4 years ago, and they never disappoint.
    More info
    Myron's at Alon Town CenterPrice: Expensive• Steak• North San Antonio
    4.9
  • DeborahVIP
    San Antonio •47 reviews
    5.0
    Dined 4 days ago
    We had such a good experience last year on Valentines Day that we made reservations again this year. The place was absolutely slammed, and we had a bit of a wait even with reservations. But the people at the host stand were great, even handing out glasses of champagne to those who were waiting. We got a booth in the bar (our favorite area) and were served by Austin, our favorite server. We shared a caesar salad, filet and lobster and a bottle of Sea Sun Pinot noir. Everything was so good! A really enjoyable experience.
    More info
    Seasons 52 - San AntonioPrice: Expensive• American• Alamo Heights
    4.8
  • Linda
    San Antonio •2 reviews
    5.0
    Dined on 25 Dec 2024
    The waitress was very attentive to our needs. I felt sorry that she had to work on Christmas Day.
    More info
    Red Lobster - San Antonio - NW Loop 410Price: Moderate• Seafood• North San Antonio
    4.4
  • Privacy policy
  • Terms of Use
  • Impressum
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable International Ltd. Alphabeta Building, 14-18 Finsbury Square, London EC2A 1AH - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo