Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Francisco Bay Area

Best Southwest American Restaurants in Mission District

Price
Regions
Areas
Top Rated
Dining Options
Seating options
Award-winning
Accessibility

150 restaurants available nearby

A photo of Curio restaurant
4.2
Awesome(307)
Price: Moderate
• Mexican • Mission District
Booked 9 times today
Curio, located in the vibrant Mission District of San Francisco, offers an exceptional Contemporary American dining experience. This eclectic bar and restaurant skillfully merges regional American cuisine with a flair for the unconventional, creating a menu that delights and surprises. Reviewers rave about the “unique and flavorful” dishes, highlighting the perfectly cooked burgers and tender braised short ribs. The atmosphere is enriched by “awesome cocktails and food,” along with live music that elevates the dining experience. With excellent service and a seamless connection to the neighboring venue, The Chapel, Curio ensures a memorable night filled with culinary and cultural pleasures.
A photo of Tacolicious - Mission District restaurant
4.5
Awesome(94)
Price: Moderate
• Mexican • Mission District
Booked 13 times today
Tacolicious in the Mission District of San Francisco is a vibrant destination for Contemporary Mexican cuisine that truly shines with authenticity and quality. Diners rave about the "excellent tacos and bowls," highlighting the variety, including vegetarian options like kale/potato tacos and mushroom carnitas. The restaurant’s dedication to fresh, responsibly sourced ingredients ensures "delicious and fresh" dishes that resonate with flavor. Tacolicious doesn't just serve food; it offers a memorable experience, with a "festive environment" and "friendly staff" that make every visit special. Whether you're enjoying a "sunny outdoor patio" or indulging in their "amazing churros," Tacolicious promises a delightful culinary journey.
A photo of House of Prime Rib restaurant
4.8
Exceptional(15962)
Price: Very Expensive
• Mexican • Civic Center / Hayes Valley / Van Ness
Booked 243 times today
House of Prime Rib in San Francisco is a beacon of authentic American cuisine, renowned for its "iconic" status and exceptional prime rib. With 62 years of unwavering dedication, it’s no surprise that this establishment garners glowing praise from loyal patrons who rave about its "festive" atmosphere and "superb" service. Guests continually highlight the "delicious" prime rib, which is described as "massive" and "perfectly cooked," making every visit a memorable experience. The lively ambiance and the meticulous attention from the staff ensure that every meal feels like a special occasion. Truly, House of Prime Rib offers a quintessential American dining experience.
A photo of Tartine Manufactory - San Francisco restaurant
4.7
Exceptional(1036)
Price: Expensive
• Mexican • Mission District
Booked 24 times today
Tartine Manufactory in San Francisco’s vibrant Mission District is a beacon of authentic American cuisine, celebrated for its mastery of artisanal bread and world-class sourdough pizza. Diners rave about the restaurant’s "outstanding" food and "fantastic" service, emphasizing the quality of its market-driven, seasonal menu. The pizzas, described as "some of the best in the city," showcase a true American culinary flair with unique toppings and a perfect crust. The atmosphere is equally inviting, with a "lovely, airy space" and a laid-back vibe that makes every visit a special occasion. Tartine Manufactory is a must-visit for anyone craving genuine American flavors.
A photo of Fable - SF restaurant
4.6
Exceptional(2208)
Price: Moderate
• Mexican • The Castro
Booked 39 times today
Nestled in the heart of San Francisco's vibrant Castro neighborhood, Fable - SF is a true gem for Contemporary American cuisine lovers. The restaurant’s seasonal California dishes are hailed as "delicious" and "scrumptious," promising an authentic taste of contemporary culinary artistry. The charming garden patio, often described as "gorgeous" and "beautiful," offers a unique outdoor dining experience that perfectly complements the exquisite dishes. With friendly and efficient staff, Fable ensures a warm and inviting atmosphere where every meal feels like a special occasion. Whether you're enjoying brunch or dinner, Fable's commitment to quality and freshness makes it an unforgettable dining destination.
A photo of The Progress restaurant
4.8
Exceptional(2509)
Price: Very Expensive
• Mexican • Western Addition
Booked 54 times today
The Progress in Western Addition, San Francisco, offers a truly remarkable Californian dining experience. Celebrated for its "innovative menu" and "delicious flavors," this restaurant uses entirely local ingredients to craft dishes that highlight the essence of Californian cuisine. Guests rave about the duck, described as a "must-try" and "100% juicy and tender," alongside other inventive dishes like the seaweed noodles and Tierra vegetables masa dumplings. The ambiance is "casual and playful," providing the perfect setting for what many reviewers describe as "the best meal in SF." With excellent service and a creative menu, The Progress is an unmissable culinary gem.
A photo of Frances restaurant
4.9
Exceptional(3671)
Price: Very Expensive
• Mexican • The Castro
Booked 16 times today
Frances, nestled in the heart of The Castro in San Francisco, is a beacon of Contemporary American cuisine, celebrated for its vibrant and innovative dishes. Chef Melissa Perello’s seasonal menu masterfully showcases "California Cuisine," emphasizing fresh, locally sourced ingredients that "speak for themselves." Diners rave about the "phenomenal" short rib and "divine" house sourdough, noting the harmonious blend of flavors that elevate each dish. The restaurant’s ambiance is described as cozy yet elegant, making it a perfect spot for special occasions. With its "exemplary" service and carefully curated wine pairings, Frances offers an unforgettable dining experience that keeps patrons returning for more.
A photo of Firefly Restaurant restaurant
4.9
Exceptional(3029)
Price: Expensive
• Mexican • Noe Valley
Booked 19 times today
Firefly Restaurant in Noe Valley, San Francisco, is a shining beacon of authentic American cuisine. With its innovative and ever-evolving menu, Firefly delivers "mind blowing" dishes that perfectly capture the essence of American flavors while catering to diverse palates. Known for its "delicious, healthy, perfectly portioned" offerings, this neighborhood gem consistently delights diners with its creative combinations, including standout dishes like fried chicken and Brussel sprouts. The cozy, welcoming atmosphere, combined with a "warm, efficient" service, ensures a memorable dining experience. Firefly truly embodies the heart and soul of American dining, making it a must-visit destination for food enthusiasts.
A photo of The Palm Court at RH San Francisco restaurant
4.8
Exceptional(1829)
Price: Very Expensive
• Mexican • Potrero Hill / Dogpatch
Booked 111 times today
The Palm Court is located in RH San Francisco's Gallery at the Historic Bethlehem Steel Building. Recalling the distinctive glamour of San Francisco's Gilded Age, the stunning statement space is sheathed in Italian Calacatta gold marble and features a cascading center fountain, towering Medjool date palms and glimmering chandeliers. Adjacent to the restaurant, two luminous wine bars offer exceptional wines and Champagnes from around the world.For group dining inquiries, please email: sfhospitality@rh.com
A photo of The Rotunda at Neiman Marcus - San Francisco restaurant
4.8
Exceptional(6189)
Price: Expensive
• Mexican • Downtown / Union Square
Booked 115 times today
The Rotunda at Neiman Marcus in San Francisco is a shining example of exquisite American cuisine, offering a dining experience that combines tradition and elegance. Nestled in the heart of Union Square, this iconic venue is beloved for its "excellent service" and "delicious food," consistently leaving diners "extremely satisfied." The Rotunda's menu is celebrated for its innovative takes on American classics, like the "wonderful French 75 cocktail and lobster club sandwich." The chic setting, complete with beautiful views and festive decorations, enhances the atmosphere, making it a "must-visit" destination, especially during the holiday season. Experience the quintessential American dining delight at The Rotunda!

How is content generated

See what locals rave about

From verified diners like you
From verified diners like you

Discover best Mexican / Southwestern restaurants in Mission District

Discover the vibrant and diverse Mexican dining options available in San Francisco's Mission District, an area renowned for its rich culinary scene. This neighborhood offers an array of Mexican restaurants that cater to a variety of tastes and preferences, from traditional dishes that evoke the flavors of Mexico to innovative culinary creations that blend modern techniques with classic recipes. Each restaurant in the Mission District emphasizes authentic, high-quality ingredients, ensuring a delightful dining experience for aficionados of Mexican cuisine. Whether you're looking for a cozy spot for a casual meal or a sophisticated venue for a special occasion, the Mission District has something to offer. Patrons can expect excellent service, a warm atmosphere, and, most importantly, mouth-watering Mexican food that keeps locals and tourists coming back. The dining scene here is a dynamic mix of old and new, making it a must-visit destination for anyone craving genuine Mexican flavors in the heart of San Francisco.

  • Privacy policy
  • Terms of Use
  • Impressum
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable International Ltd. Alphabeta Building, 14-18 Finsbury Square, London EC2A 1AH - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo